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BEEM Journal

BEEM Journal Catalog

  • Volume 6 (2021)

    • Issue 604 (April 2021)

      • 210401
        Is ibuprofen superior to acetaminophen for treatment of fever in children younger than 2 years?
      • 210402
        In patients presenting with cannabis hyperemesis syndrome (CHS), is haloperidol more effective compared to ondansetron for reducing pain and nausea?
    • Issue 603 (March 2021)

      • 210301
        What is the effect of prednisolone in preschool children with wheeze associated with acute respiratory illness?
      • 210302
        Is low-dose ketamine as effective and safe as morphine for analgesia in the emergency department?
      • 210303
        What is the risk of overcorrection of symptomatic hyponatremia with rapid intermittent bolus (RIB) versus slow continuous infusion (SCI) of hypertonic saline?
      • 210304
        Can application of the YEARS algorithm safely exclude pulmonary embolism?
    • Issue 602 (February 2021)

      • 210201
        From a patient's perspective, are antibiotics "just as good as" surgery for appendicitis?
      • 210202
        What is the safety profile of ceftriaxone in pediatric patients, as determined by the frequency and type of adverse drug reactions documented in the published literature?
      • 210203
        What are the latest guidelines for the diagnosis of acute aortic syndrome?
      • 210204
        Does tranexamic acid reduce mortality from acute traumatic brain injury?
    • Issue 601 (January 2021)

      • 210101
        Is a single troponin measurement below the level of detection superior to serial troponin measurements for the safe discharge of chest pain patients?
      • 210102
        How does chest ultrasonography compare to supine chest radiography for the diagnosis of pneumothorax in trauma patients?
      • 210103
        Is intranasal ketamine effective for the treatment of acute pain in children?
      • 210104
        How do NSAIDs compare with other oral analgesics for treating acute soft tissue injuries?
  • Volume 5 (2020)

    • Issue 512 (December 2020)

      • 201201
        Which variables are most associated with potentially missed appendicitis in the emergency department?
      • 201202
        What are the effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding?
      • 201203
        Do patients with severe COVID-19 benefit from the addition of dexamethasone to usual care?
      • 201204
        Is antacid therapy alone more effective than combined with lidocaine in relieving epigastric pain?
    • Issue 511 (November 2020)

      • 201101
        Are older adults taking direct oral anticoagulants at higher risk of hospital admission for hemorrhage with clarithromycin than with azithromycin?
      • 201102
        Is the combination of ibuprofen and acetaminophen for pediatric pain superior to either analgesic alone?
      • 201103
        Does the addition of ticagrelor to aspirin reduce the risk of ischemic events following mild acute ischemic stroke or high-risk transient ischemic attack?
      • 201104
        What is the risk of cardiovascular death among adults within days of a dispensed azithromycin prescription?
    • Issue 510 (October 2020)

      • 201001
        Which is the optimum second-line therapy for adults and children with benzodiazepine-refractory convulsive status epilepticus?
      • 201002
        How do N95 respirators compare to medical masks for preventing viral respiratory infections in healthcare workers?
      • 201003
        Does the addition of N-terminal pro–B-type natriuretic peptide measurement to the Canadian Syncope Risk Score improve the prediction of 30-day serious adverse events in emergency department patients presenting with syncope?
      • 201004
        Is there an association between pain, opioid treatment, and delirium in older adults in the emergency department?
    • Issue 509 (September 2020)

      • 200901
        Which antibiotics commonly prescribed for acute otitis media are associated most with adverse events?
      • 200902
        Is first attempt at pediatric lumbar puncture more successful with ultrasound guidance?
      • 200903
        Is the Canadian Syncope Risk Score a valid clinical prediction tool for use in the emergency department?
      • 200904
        For cardioversion of atrial fibrillation, is a strategy of drug–shock more effective than a shock-only and does pad placement make a difference?
    • Issue 508 (August 2020)

      • 200801
        What is the clinical impact of the Ottawa subarachnoid hemorrhage rule and the 6-hour-computed tomography rule on investigation rates?
      • 200802
        Is repeated antibiotic exposure associated with an increased body mass index by 4.5 years old?
      • 200803
        Is conservative treatment for primary spontaneous pneumothorax noninferior to interventional treatment?
      • 200804
        Does surgical repair within 6 hours of hip fracture diagnosis decrease mortality and major adverse events?
    • Issue 507 (July 2020)

      • 200701
        Which of the 4 published decision aids provides the highest sensitivity to rule-out myocardial infarction and major adverse cardiac events?
      • 200702
        Does oxygen via high-flow nasal cannula improve symptom relief compared to conventional oxygen therapy in palliative patients presenting with acute hypoxemic respiratory failure?
      • 200703
        What is the diagnostic utility of troponin testing in elderly patients with nonspecific complaints?
      • 200704
        Does application of the Feverkidstool reduce antibiotic prescritions for children with respiratory infections?
    • Issue 506 (June 2020)

      • 200601
        Does irrigation with 20 minutes of cool running water reduce the need for skin grafts in children with burns?
      • 200602
        How frequently do emergency physician pediatric musculoskeletal radiograph interpretations differ from radiologist interpretations and lead to adverse events?
      • 200603
        What are the potential benefits and harms of suturing mammalian bite wounds?
      • 200604
        Is the time to recovery from influenza-like illness reduced by adding oseltamivir to usual care?
    • Issue 505 (May 2020)

      • 200501
        Can pulmonary embolism be ruled out through a combination of clinical assessment and d-Dimer testing?
      • 200502
        What are the latest guidelines for cardiopulmonary resuscitation following pediatric cardiac arrest?
      • 200503
        Does antibiotic treatment of asymptomatic bacteriuria in pregnancy reduce the development of pyelonephritis and associated risk of low birthweight and preterm birth?
      • 200504
        What are the latest guidelines for the early management of acute ischemic stroke?
    • Issue 504 (April 2020)

      • 200401
        Are patients with atrial fibrillation discharged sooner after electrical or chemical cardioversion first?
      • 200402
        Does induced hypothermia (33°C during the first 24 hours) improve neurologic outcomes in patients with cardiac arrest and non-shockable rhythm?
      • 200403
        What are the latest recommendations for assessing adult patients with acute nontraumatic headache?
      • 200404
        Is a 0/1-hour high-sensitivity cardiac troponin T protocol noninferior to a 0/3-hour protocol in ruling out acute coronary syndrome in emergency department patients?
    • Issue 503 (March 2020)

      • 200301
        What are the effects of tranexamic acid on head injury-related death, disability and adverse events in patients with acute traumatic brain injury?
      • 200302
        Does the addition of nonsteroidal anti-inflammatory drugs and codeine to paracetamol (acetaminophen) produce superior analgesia for acute musculoskeletal injuries?
      • 200303
        Do ibuprofen doses greater than 400 mg provide more effective analgesia at 60 minutes?
      • 200304
        Does C-Reactive Protein testing for chronic obstructive pulmonary disease exacerbations reduce antibiotic use without harm?
    • Issue 502 (February 2020)

      • 200201
        Is the incidence of influenza less in healthcare personnel wearing N95 respirator masks than those wearing standard medical/surgical masks?
      • 200202
        Is sodium polystyrene sulfonate use associated with a higher risk of serious adverse gastrointestinal events at 30 days?
      • 200203
        Is penicillin V four times daily for five days as effective as three times daily for 10 days for group A streptococci pharyngotonsillitis?
      • 200204
        What are the 2019 recommendations for the diagnosis and treatment of community-acquired pneumonia in adults?
    • Issue 501 (January 2020)

      • 200101
        Does avoidance of antibiotic therapy for uncomplicated diverticulitis result in increased adverse outcomes in the longterm?
      • 200102
        How well do specific electrocardiogram and high-sensitivity cardiac troponin criteria identify acute myocardial infarction in patients presenting with chest discomfort and a left bundle branch block?
      • 200103
        What is the incidence of unrecognized delirium in emergency departments and its impact on resources, patient function, and cognition at 60 days?
      • 200104
        Does buddy taping boxer’s fractures provide better functional outcome than plaster immobilization?
  • Volume 4 (2019)

    • Issue 412 (December 2019)

      • 191201
        What are the factors associated with fever phobia in caregivers and healthcare providers?
      • 191202
        Does thrombolysis benefit patients with favorable perfusion imaging 4.5–9 hours after stroke onset?
      • 191203
        How well does the extended Focused Assessment with Sonography in Trauma (eFAST) exam detect pneumothoraces, pericardial effusions, and intra-abdominal free fluid in injured patients?
      • 191204
        Are prednisolone and/or low-dose dexamethasone noninferior to standard-dose dexamethasone for croup?
    • Issue 411 (November 2019)

      • 191101
        Is nasal compression with tranexamic acid superior to simple nasal compression and or Merocel packing for cessation of bleeding from anterior epistaxis?
      • 191102
        Can ultrasonography detect pediatric elbow fractures?
      • 191103
        Does dextrose in intravenous fluids benefit dehydrated children?
      • 191104
        Can high-sensitivity troponin values at emergency department presentation help predict MI and 30-day outcomes?
    • Issue 410 (October 2019)

      • 191001
        What is the safety and effectiveness of non-invasive positive pressure ventilation compared to standard medical care for acute cardiogenic pulmonary edema?
      • 191002
        How effective is lithium compared to other treatments for acute mania?
      • 191003
        What is the risk of thrombosis in non-surgical patients treated with systemic tranexamic acid?
      • 191004
        Can a pregnancy-adapted algorithm safely avoid diagnostic imaging in pregnant women with suspected pulmonary embolism?
      • 191005
        Is Tramadol safe and effective for the treatment of osteoarthritis?
    • Issue 409 (September 2019)

      • 190901
        What is the diagnostic yield of computed tomography for patients presenting to the ED with syncope or patients hospitalized for syncope?
      • 190902
        Does bedside dynamic ultrasonography increase successful peripheral intravenous access rates?
      • 190903
        Is point-of-care ultrasound accurate for diagnosing shoulder dislocation compared to X-ray?
      • 190904
        How is acute lower gastrointestinal bleeding best diagnosed and managed?
      • 190905
        Which clinical findings best indicate a cardiac or non-cardiac cause of syncope?
    • Issue 408 (August 2019)

      • 190801
        What proportion of syncopal episodes are caused by pulmonary embolism?
      • 190802
        Is a wait-and-see approach noninferior to early cardioversion in achieving sinus rhythm 4 weeks after an emergency department visit for new-onset, symptomatic atrial fibrillation?
      • 190803
        What are the relative risks of stroke and bleeding in patients with paroxysmal versus sustained (persistent or permanent) atrial fibrillation who take oral anticoagulants?
      • 190804
        What is the accuracy of lung ultrasonography compared to X-ray for the diagnosis of cardiogenic pulmonary edema in patients presenting with dyspnea?
    • Issue 407 (July 2019)

      • 190701
        What are the benefits and harms of intravenous maintenance fluids for children?
      • 190702
        Does delayed antibiotic treatment for elderly patients with suspected urinary tract infection (UTI) increase severe adverse outcomes?
      • 190703
        What are the benefits and harms of different types of immobilization for common distal radius fractures in children?
      • 190704
        Does bag-mask ventilation decrease the low oxygen saturation during endotracheal Intubation?
    • Issue 406 (June 2019)

      • 190601
        Does the HEART score predict major adverse cardiac events in emergency department chest pain patients?
      • 190602
        Can patients with suspected opioid overdose be safely discharged 1-hour after naloxone administration?
      • 190603
        Does early invasive coronary angiography and revascularization in patients with non-ST-segment elevation acute coronary syndrome within 12 hours of diagnosis reduce adverse outcomes?
      • 190604
        Which antiarrhythmic drug therapy is best for pediatric shock-refractory ventricular fibrillation/pulseless ventricular tachycardia cardiac arrest?
      • 190605
        Which physical findings best predict difficult endotracheal intubation?
    • Issue 405 (May 2019)

      • 190501
        Does clopidogrel with aspirin compared to aspirin alone given in the first 24 hours after a high-risk transient ischemic attack or minor ischemic stroke reduce recurrent stroke and death?
      • 190502
        Does premedication with midazolam or haloperidol of adults undergoing procedural sedation reduce ketamine-associated agitation?
      • 190503
        Are intranasal ketamine and fentanyl similarly effective in the treatment of acute pediatric limb pain?
      • 190504
        Which interventions are most effective for emergency contraception?
      • 190505
        Do probiotics improve symptoms in children with acute moderate-to-severe gastroenteritis?
    • Issue 404 (April 2019)

      • 190401
        Do antiarrhythmic drugs benefit patients with shockable cardiac arrest?
      • 190402
        What are the frequency and associated short-term, adverse outcomes in high-risk patients of nonsteroidal anti-inflammatory drug prescriptions?
      • 190403
        What are the benefits and risks of dual antiplatelet treatment for acute minor ischemic stroke or high risk transient ischemic attack?
      • 190404
        Can acetaminophen reduce febrile seizure recurrences during the same fever episode?
      • 190405
        Can point-of-care ultrasound more accurately identify the cricothyroid membrane in patients with poorly defined neck anatomy than external palpation?
    • Issue 403 (March 2019)

      • 190301
        Do critically ill people in need of fluid resuscitation benefit more from colloids or crystalloids?
      • 190302
        Is 72-hour survival in adults with out-of-hospital cardiac arrest greater with initial endotracheal intubation or laryngeal tube insertion?
      • 190303
        In out-of-hospital cardiac arrest patients, does a supraglottic airway device improve favorable functional outcome at 30 days compared with endotracheal intubation?
      • 190304
        Does the HEART Pathway identify patients at low risk of a major adverse cardiac event at 1-year without increasing health care utilization?
      • 190305
        Do patients with uncomplicated acute rhinosinusitis benefit from antibiotic treatment?
      • 190306
        Do antiarrhythmic drugs benefit patients with shockable cardiac arrest?
    • Issue 402 (February 2019)

      • 190201
        Is bag-mask ventilation during out-of-hospital cardiorespiratory arrest noninferior to endotracheal intubation for favorable neurological outcome?
      • 190202
        Is treatment of central venous thrombosis more effective and safer with low-molecular weight or unfractionated heparin?
      • 190203
        Does the prehospital administration of thawed plasma reduce mortality in trauma patients at risk for hemorrhagic shock?
      • 190204
        Is ketamine an effective alternative to parenteral opioids for the treatment of acute pain?
      • 190205
        Does pelvic examination improve the diagnosis of sexually transmitted disease in young females?
      • 190206
        Is epinephrine a safe and effective treatment for cardiac arrest?
      • 190207
        How effective are glucocorticoids for the treatment of croup in children?
      • 190208
        Does abscess incision and drainage with point-of-care ultrasonography reduce clinical failure?
    • Issue 401 (

      January 2019

      )

      • 190101
        Does use of a bougie improve first-attempt emergency intubation success in difficult airway patients?
      • 190102
        Can computed tomographic pulmonary angiography safely exclude pulmonary embolism?
      • 190103
        Which vasopressors are associated with the best outcomes for adults in cardiac arrest?
      • 190104
        Can bedside airway examination screening tests detect difficult to manage airways in the presence of normal anatomy?
      • 190105
        Do patients with low-risk pulmonary embolism discharged early on rivaroxaban require fewer hospitalization days compared to standard of care?
      • 190106
        Do balanced crystalloids versus saline decrease the risk of adverse outcome events in noncritically ill adults?
  • Volume 3 (2018)

    • Issue 312 (December 2018)

      • 181201
        Is there benefit of antibiotics following incision and drainage of uncomplicated skin abscesses?
      • 181202
        How accurate is the urinalysis for urinary tract infections in febrile infants 60 days and younger?
      • 181203
        Does oseltamivir within 48 hours of influenza symptom onset in children reduce the time to symptom resolution?
      • 181204
        Does intravenous fluid infusion rate or composition affect neurologic outcomes in children with diabetic ketoacidosis?
      • 181205
        Does slow infusion reduce the associated dysphoric side effects of ketamine?
      • 181206
        Are Pigtail catheters as safe and effective as chest tubes for the initial treatment of pneumothorax?
    • Issue 311 (November 2018)

      • 181101
        Does cross-checking cases with another physician reduce the emergency department adverse event rate?
      • 181102
        Is QTc prolongation in poisoned patients associated with an increased risk of death?
      • 181103
        Does application of the pulmonary embolism rule-out criteria rule result in an inferior rate of thromboembolic events over 3 months among very low-risk patients with suspected pulmonary embolism?
      • 181104
        Does tamsulosin promote ureteral stone expulsion?
      • 181105
        How accurate is chest ultrasonography for the diagnosis of pneumothorax and hemothorax in adult trauma patients?
    • Issue 310 (October 2018)

      • 181001
        Do balanced crystalloids versus saline decrease the risk of adverse outcome events in critically ill adults?
      • 181002
        Is honey an effective treatment for acute cough in children?
      • 181003
        In acute ischemic stroke and high-risk transient ischemic attack patients, does the addition of clopidogrel to daily aspirin reduce the risk of major ischemic vascular events at 90 days?
      • 181004
        Is trimethoprim for urinary tract infection associated with increased adverse events in the elderly?
      • 181005
        Is there an association between fasting before procedural sedation and adverse events in children?
    • Issue 309 (September 2018)

      • 180901
        Can antidotes be delivered via the intraosseous route?
      • 180902
        Do systemic methicillin-resistant Staphylococcus aureus-active antibiotics improve cure rates following abscess incision and drainage?
      • 180903
        What is the optimal treatment of superficial thrombophlebitis of the legs in relieving symptoms and preventing venous thromboembolism?
      • 180904
        Are alpha-blockers effective as medical expulsive therapy for ureteral stones?
    • Issue 308 (August 2018)

      • 180801
        What are the effects of nebulized hypertonic saline solution (≥ 3%) in reducing morbidity in children up to 24 months of age with acute bronchiolitis?
      • 180802
        Is supplemental oxygen beneficial for normoxic patients with acute myocardial infarction?
      • 180803
        In patients presenting to the emergency department with syncope, what is the prevalence of pulmonary embolism and venous thromboembolism at first evaluation and within 90 days?
      • 180804
        Is high-velocity nasal insufflation less effective than noninvasive positive-pressure ventilation in the treatment of emergency department patients with respiratory failure?
      • 180805
        How accurate is computed tomography in the diagnosis of intra-abdominal injuries in stable patients with anterior abdominal stab wounds?
      • 180806
        How beneficial and safe Is liberal versus conservative supplemental oxygen for acutely ill adults?
    • Issue 307 (July 2018)

      • 180701
        What is the epidemiology of bacteremia in febrile infants aged 60 days and younger?
      • 180702
        Is the combination of an anti-inflammatory drug with an opioid more effective for musculoskeletal injury pain in children than either agent alone?
      • 180703
        What is the comparative effectiveness of antiarrhythmics for out-of-hospital cardiac arrest for patients with refractory ventricular fibrillation?
      • 180704
        Is topical tranexamic acid effective for anterior epistaxis in patients taking antiplatelet therapy?
      • 180705
        Does early treatment with high-flow oxygen therapy in infants with bronchiolitis and hypoxemia reduce the escalation of care?
    • Issue 306 (June 2018)

      • 180601
        Is morphine superior to ibuprofen for relieving children’s pain at home, after minor orthopedic surgery?
      • 180602
        Does tamsulosin effectively and safely facilitate passage of large, distal ureteric stones?
      • 180603
        What is the risk for emergency neurosurgery or death in children with isolated skull fractures?
      • 180604
        Do intravenous sodium bicarbonate or sodium chloride with oral acetylcysteine or placebo prevent acute kidney injury and major adverse outcomes in high-risk patients undergoing angiography?
      • 180605
        Is 2 days of dexamethasone for children with acute asthma less effective than 5 days of prednisone?
    • Issue 305 (May 2018)

      • 180501
        Is point-of-care ultrasound during resuscitation associated with delays in chest compressions?
      • 180502
        Are there benefits or harms in treating asymptomatic bacteriuria?
      • 180503
        Can the Testicular Workup for Ischemia and Suspected Torsion score risk stratify pediatric males with acute scrotum?
      • 180504
        Is the Broselow tape an accurate weight-estimation instrument and effective drug-dosing guide for pediatric emergencies?
    • Issue 304 (April 2018)

      • 180401
        Does a combination of ibuprofen and acetaminophen provide similar pain reduction to a combination of acetaminophen and an opioid for emergency department patients with acute extremity pain?
      • 180402
        Can symptoms and physical examination findings identify children with radiographic pneumonia?
      • 180403
        Does apneic oxygenation increase the average lowest oxygen saturation during rapid sequence intubation?
      • 180404
        Is Coronary CT angiography superior to standard-of-care for detecting atherosclerotic disease in patients with acute chest pain?
    • Issue 303 (March 2018)

      • 180301
        In patients with suspected myocardial infarction without hypoxemia, what is the effect of routine oxygen therapy compared to ambient air on mortality?
      • 180302
        Can complete blood cell counts accurately identify febrile infants with bacteremia or bacterial meningitis?
      • 180303
        What are the benefits and harms of using corticosteroids as an adjunct treatment for sore throat?
      • 180304
        How well does the Ottawa Subarachnoid Hemorrhage Rule detect or rule out subarachnoid hemorrhage?
    • Issue 302 (February 2018)

      • 180201
        What is the risk of acute kidney injury, renal replacement therapy, and mortality after computed tomography with intravenous contrast compared with computed tomography without use of contrast?
      • 180202
        Which medications are associated with adverse events in procedural sedation for children?
      • 180203
        Does oral prednisolone reduce symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection?
      • 180204
        How well does bivalve cast immobilization maintain reduction of pediatric displaced forearm fractures?
    • Issue 301 (January 2018)

      • 180101
        Does focused assessment with sonography for trauma examination decrease the rate of abdominal computed tomography scans in hemodynamically stable pediatric patients with blunt torso trauma?
      • 180102
        Does oxygen via nasal cannula during the apneic period of endotracheal intubation reduce hypoxemia?
      • 180103
        Which is the most effective and least harmful method of reducing pulled (nursemaid’s) elbow?
      • 180104
        Is haloperidol an effective single agent treatment for psychosis-induced aggression or agitation?
  • Volume 2 (2017)

    • Issue 212 (December 2017)

      • 171201
        Is modified Valsalva maneuver more effective than the standard Valsalva maneuver in terminating paroxysmal supraventricular tachycardia?
      • 171202
        Which compression-to-ventilation methods for cardiac arrest are associated with better outcomes?
      • 171203
        Does nebulized 3% hypertonic saline treatment in the emergency department reduce the rate of hospital admissions among infants with a first episode of acute bronchiolitis?
      • 171204
        Can high-flow nasal cannula oxygen reduce respiratory rate in patients with cariogenic pulmonary edema?
    • Issue 211 (November 2017)

      • 171101
        Do critically ill adults requiring vasopressor support benefit from a higher target mean arterial pressure?
      • 171102
        Do femoral nerve blocks reduce acute pain and use of opioids in elderly patients with hip fractures?
      • 171103
        Does more rapid sepsis treatment reduce in-hospital mortality?
      • 171104
        Does the addition of Trimethoprim-Sulfamethoxazole to Cephalexin improve the clinical cure of cellulitis?
    • Issue 210 (October 2017)

      • 171001
        Does oral dexamethasone without antibiotic increase acute sore throat symptom resolution in adults?
      • 171002
        Does early administration of tranexamic acid reduce death in women with post-partum hemorrhage?
      • 171003
        What is the rate of traumatic intracranial hemorrhage from a ground-level fall in patients taking antithrombotic therapy?
      • 171004
        Does procedural sedation with ketofol produce fewer recovery reactions than ketamine?
    • Issue 209 (September 2017)

      • 170901
        Does early goal-directed therapy reduce mortality among patients with severe sepsis or septic shock?
      • 170902
        Do intravenous first-line benzodiazepines terminate seizures faster than non-intravenous routes?
      • 170903
        Does the Quick-Wee method facilitate faster clean catch urine collection in infants?
      • 170904
        Does needle aspiration for spontaneous pneumothorax reduce hospital length-of-stay compared to chest tube drainage?
      • 170905
        Which head injury decision rule for children is most accurate?
    • Issue 208 (August 2017)

      • 170801
        Which clinical findings can best rule in/out acute appendicitis in children?
      • 170802
        Do patients presenting to the emergency department with chest pain require cardiac monitoring?
      • 170803
        How accurate is point-of-care focused echocardiography in predicting outcome of resuscitation in cardiac arrest patients?
      • 170804
        Is ketamine an effective adjunct for acute pain in the emergency department?
      • 170805
        Which early rule-out strategy for early rule-out acute myocardial infarction using high-sensitivity cardiac troponin I should be favored for clinical implementation in routine care?
    • Issue 207 (July 2017)

      • 170701
        How effective is high-flow nasal cannula therapy at preventing endotracheal intubation in adults?
      • 170702
        Do patients undergoing intravenous contrast-enhanced computed tomography experience increased incidence of acute kidney injury?
      • 170703
        Is Ketamine effective at reducing pain over 120 minutes when used as an adjunct to opioid therapy?
      • 170704
        Does the addition of diazepam to naproxen improve low back pain and improve functional outcomes?
      • 170705
        Does emergency physician prescribing of opioids contribute to patient long-term opioid use?
      • 170706
        Do patients treated in hospital for community-acquired pneumonia benefit from the addition of corticosteroid therapy?
    • Issue 206 (June 2017)

      • 170601
        What are the most recent recommendations for management of carbon monoxide poisoning?
      • 170602
        What is the comparative effectiveness of 10, 15, and 30 mg of intravenous ketorolac in reducing pain at 30 minutes in patients presenting to the emergency department acute pain?
      • 170603
        How well do the European Society of Cardiology pathway and High-STEACS algorithm rule out acute myocardial infarction?
      • 170604
        What is the accuracy of point-of-care ultrasound in diagnosing abscess in emergency department patients with skin and soft tissue infections compared to standard care?
      • 170605
        Is there benefit to combining inhaled beta-agonist and anticholinergic agents for the emergency management of adults with asthma?
    • Issue 205 (May 2017)

      • 170501
        Is it safe to rule out acute pulmonary embolism with stand-alone D-dimer testing below 750 µg/L?
      • 170502
        Can patients with large ureteric stones benefit from treatment with alpha-blockers?
      • 170503
        What is the effectiveness of shared decision-making facilitated by a decision aid in patients with low-risk chest pain?
      • 170504
        Is therapeutic hypothermia beneficial for traumatic brain Injury in adult and pediatric patients?
      • 170505
        How well does of point-of-care-ultrasound identify pediatric forearm fractures?
    • Issue 204 (April 2017)

      • 170401
        What are the target hemoglobin levels for red blood cell transfusion among hemodynamically stable adult patients?
      • 170402
        In older adults with a hip fracture, does a regional femoral nerve block in the emergency department followed by a continuous fascia iliaca block by anesthesiologist improve pain control and walking abilities?
      • 170404
        Which is the most effective reduction maneuver for nursemaid’s elbow in toddlers?
      • 170405
        What are the most recent recommendations for the management of antithrombotic-associated intracranial hemorrhage?
    • Issue 203 (March 2017)

      • 170301
        What is the prevalence of pulmonary embolism among patients with acute exacerbations of chronic obstructive pulmonary disease?
      • 170302
        What are the key recommendations for evaluation of adult patients with suspected transient ischemic attack in the emergency department?
      • 170303
        In a meta-analysis of patients with a confirmed diagnosis of ureteral stone, is tamsulosin more effective than placebo in improving stone passage?
      • 170304
        Is there benefit from percutaneous coronary intervention for post-arrest patients without ST-elevation myocardial infarction?
      • 170305
        In patients with severe sepsis, does hydrocortisone prevent progression to septic shock?
      • 170403
        What is the prevalence of pulmonary embolism in patients admitted to hospital for first-time syncope?
    • Issue 202 (February 2017)

      • 170202
        Does a 1:1 ratio, mixed combination of propofol and ketamine result in fewer adverse respiratory events than propofol alone for adult patients requiring procedural sedation and analgesia?
      • 170203
        Can a low concentration of high-sensitivity cardiac troponin T at emergency department presentation, combined with the history and electrocardiogram rule out major adverse cardiac events within 30 days?
      • 170204
        In adult patients requiring urgent reversal of warfarin, do prothrombin complex concentrates and fresh frozen plasma result in different rates of all-cause mortality?
      • 170205
        What is the efficacy of amiodarone on survival after cardiac arrest compared to lidocaine or placebo?
    • Issue 201 (January 2017)

      • 170101
        Which patient characteristics and investigations are most accurate for diagnosing subarachnoid hemorrhage?
      • 170102
        Are procainamide and amiodarone effective for terminating well-tolerated ventricular tachycardia?
      • 170103
        Is video laryngoscopy superior to direct laryngoscopy for the endotracheal intubation of critically ill patients?
      • 170104
        Is the “Step-by-Step” approach to manage young febrile infants effective?
      • 170105
        Do corticosteroids improve recovery of facial motor function in patients with Bell’s palsy?
      • 170201
        What are the effects of amiodarone on survival and neurological outcome after cardiac arrest?
  • Volume 1 (2016)

    • Issue 112 (December 2016)

      • 161201
        Which is the most effective dose of intravenous ketamine for pediatric procedural sedation and analgesia in the emergency department?
      • 161202
        How should emergency physicians manage infants with brief resolved unexplained events?
      • 161203
        What are the benefits and harms of neuraminidase inhibitors for the prevention and treatment of influenza, and what was their impact on mortality during the 2009A/H1N1 influenza epidemic?
      • 161204
        What is the relative efficacy of intensive versus standard antihypertensive treatment in patients with spontaneous supratentorial intracerebral hemorrhage?
      • 161205
        What are the relative benefits and adverse effects of antibiotic therapy for otitis media with effusion aka “glue ear”?
    • Issue 111 (November 2016)

      • 161101
        What are the risks and benefits of antiepileptic drug treatment for first unprovoked seizure?
      • 161102
        What is the efficiency and failure rate of diagnostic strategies for ruling out pulmonary embolism?
      • 161103
        Are pelvic circumferential compression devices safe and effective for the treatment of pelvic fractures?
      • 161104
        Can antibiotics be used as first line therapy for uncomplicated acute appendicitis?
      • 161105
        What are the early secondary prevention benefits of aspirin after transient ischemic attack or ischemic stroke?
    • Issue 110 (October 2016)

      • 161001
        How should well-appearing children under 2 years old with fever be managed in the emergency department?
      • 161002
        Which are the most diagnostic features of infectious mononucleosis?
      • 161003
        Is a single oral dose of dexamethasone non-inferior to 5 days of oral prednisone in preventing asthma relapse?
      • 161004
        Can children with mild gastroenteritis be as effectively treated with initial oral rehydration treatment using dilute apple juice compared to oral electrolyte maintenance solution?
      • 161005
        Are alpha2-adrenergic agonists effective treatment for opioid withdrawal?
    • Issue 109 (September 2016)

      • 160901
        What are the recommendations for antibiotic stewardship?
      • 160902
        After minimizing heterogeneity in studies reporting the effectiveness of hypertonic saline in bronchiolitis, does hypertonic saline reduce hospital length-of-stay?
      • 160903
        Does a deliberately restricted laryngeal view with the GlideScope® video laryngoscope facilitate tracheal intubation?
      • 160904
        Is intra-arterial mechanical thrombectomy safe and effective in patients with ischemic stroke?
      • 160905
        Is video laryngoscopy superior to direct laryngoscopy for the endotracheal intubation of cardiac arrest patients?
    • Issue 108 (August 2016)

      • 160801
        Is diclofenac more effective at reducing pain from ureteric calculi than morphine or paracetamol?
      • 160802
        Which nonsteroidal anti-inflammatory drugs are most effective for the treatment of arthritic pain?
      • 160803
        Which benzodiazepine is most effective for the treatment of status epilepticus in children?
      • 160804
        Is the wound infection cure rate greater with clindamycin than trimethoprim-sulfamethoxazole?
      • 160805
        Does amiodarone or lidocaine improve survival to hospital discharge after out-of-hospital cardiac arrest due to shock-refractory ventricular fibrillation or pulseless ventricular tachycardia compared to placebo?
    • Issue 107 (July 2016)

      • 160701
        Does the phosphodiesterase-5 inhibitor sildenafil facilitate passage of distal ureteric stones?
      • 160702
        Can bedside sonographic measurement of optic nerve sheath diameter in the emergency department identify increased intracranial pressure?
      • 160703
        Does antibiotic therapy for non-perforated appendicitis result in more complications compared with appendectomy?
      • 160704
        Is early goal-directed therapy associated with lower mortality rates than usual care in patients with severe sepsis and septic shock?
      • 160705
        Is a single-volar digital injection of local anesthetic as effective and less painful than a double-dorsal injection?
    • Issue 106 (June 2016)

      • 160601
        What is the risk of a motor vehicle accident within 2 years of a first-time syncope?
      • 160602
        Does treatment of uncomplicated drained abscesses with trimethoprim-sulfamethoxazole reduce the need for alternate antibiotic therapy or repeat surgical drainage 7–14 days after treatment?
      • 160603
        Do prophylactic antibiotics reduce post-surgical infection for simple hand injuries?
      • 160604
        Does inhaled magnesium sulfate benefit patients with moderate to severe acute asthma?
      • 160605
        Can point-of-care testing for group A streptococci in patients presenting with pharyngitis improve appropriate antibiotic prescribing?
    • Issue 105 (May 2016)

      • 160501
        What is the comparative effectiveness of vasopressors on mortality in patients with shock?
      • 160502
        Which treatments are recommended for status epilepticus?
      • 160503
        Is prednisone as effective as indomethacin for the treatment of acute gout?
      • 160504
        Which are the best tests available to the emergency physician for diagnosing acute heart failure?
      • 160505
        Can lung ultrasonography reduce chest X-ray use in children with suspected pneumonia?
    • Issue 104 (April 2016)

      • 160401
        Does the volume of intravenous fluid administration influence the time to metabolic normalization in children with type 1 diabetes mellitus and diabetic ketoacidosis?
      • 160402
        Does ketorolac nasal spray (NS) relieve acute migraine headaches as effectively as sumatriptan NS or placebo within 2 hours?
      • 160403
        Which agents are most effective and safest for pediatric procedural sedation?
      • 160404
        What are the latest recommendations for the management of venous thromboembolism?
      • 160405
        Does targeted temperature management of successfully resuscitated cardiac arrest patients by conventional cooling methods improve neurologic outcome or survival?
    • Issue 103 (March 2016)

      • 160302
        Can serial high-sensitivity cardiac troponin T measurement results 1 hour apart accurately diagnose acute myocardial infarction in the emergency department?
      • 160303
        Can spontaneous subarachnoid hemorrhage be ruled out by modern-generation computed tomography scanning of the brain within 6 hours of acute headache onset?
      • 160304
        What are the analgesic and side effects of ketamine-propofol combination (ketofol) in comparison with propofol in procedural sedation and analgesia?
      • 160305
        Which imaging is most appropriate for emergency department patients with chest pain?
    • Issue 102 (February 2016)

      • 160202
        Does inhaling isopropyl alcohol reduce nausea?
      • 160203
        Is a delayed antibiotic prescription for acute uncomplicated respiratory tract infection less effective at reducing symptom burden than an immediate antibiotic prescription?
      • 160204
        Does early coronary computed tomography angiography identify more adult emergency department patients requiring revascularization in 30 days than standard optimal care?
      • 160205
        How well does oblique angle chest X-ray identify occult pneumothorax in trauma patients?
      • 160301
        What are the most common and serious adverse reactions to oral corticosteroids?
    • Issue 101 (January 2016)

      • 160101
        Is continuous positive airway pressure by helmet effective in the treatment of infants with bronchiolitis?
      • 160102
        Does tamsulosin 0.4 mg daily facilitate passage of distal ureteric calculi ≤ 10 mm?
      • 160103
        Does apneic oxygenation via nasal cannula increase the lowest arterial oxygen saturation experienced by patients undergoing endotracheal intubation?
      • 160104
        Is a single dose of oral dexamethasone noninferior to 3 days of oral prednisolone in the treatment of pediatric asthma exacerbations?
      • 160105
        Do patients with community-acquired pneumonia benefit from systemic corticosteroids?
      • 160201
        Are forearm torus (buckle) fractures more effectively and safely treated with rigid or non-rigid immobilization?

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