Does ketorolac nasal spray (NS) relieve acute migraine headaches as effectively as sumatriptan NS or placebo within 2 hours?

BEEM Bottom Line

Why is this study important?

This study may be beneficial to the treatment of patients with chronic migraines by offering support for ketorolac NS as an at-home abortive medication. The study supports the noninferiority of ketorolac NS versus sumatriptan NS for the treatment of migraine headaches. It may offer a needed option for those patients who cannot safely take sumatriptan.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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