Volume 1
2016
Volume 1 / Issue 101 / 160101
January 1, 2016
Is continuous positive airway pressure by helmet effective in the treatment of infants with bronchiolitis?
Volume 1 / Issue 101 / 160102
January 1, 2016
Does tamsulosin 0.4 mg daily facilitate passage of distal ureteric calculi ≤ 10 mm?
Volume 1 / Issue 101 / 160103
January 1, 2016
Does apneic oxygenation via nasal cannula increase the lowest arterial oxygen saturation experienced by patients undergoing endotracheal intubation?
Volume 1 / Issue 101 / 160104
January 1, 2016
Is a single dose of oral dexamethasone noninferior to 3 days of oral prednisolone in the treatment of pediatric asthma exacerbations?
Volume 1 / Issue 101 / 160105
January 1, 2016
Do patients with community-acquired pneumonia benefit from systemic corticosteroids?
Volume 1 / Issue 101 / 160201
February 1, 2016
Are forearm torus (buckle) fractures more effectively and safely treated with rigid or non-rigid immobilization?
Volume 1 / Issue 102 / 160202
February 1, 2016
Does inhaling isopropyl alcohol reduce nausea?
Volume 1 / Issue 102 / 160203
February 1, 2016
Infectious Disease | Respiratory Infections
Is a delayed antibiotic prescription for acute uncomplicated respiratory tract infection less effective at reducing symptom burden than an immediate antibiotic prescription?
Volume 1 / Issue 102 / 160204
February 1, 2016
Cardiovascular | Acute Coronary Syndrome
Does early coronary computed tomography angiography identify more adult emergency department patients requiring revascularization in 30 days than standard optimal care?
Volume 1 / Issue 102 / 160205
February 1, 2016
How well does oblique angle chest X-ray identify occult pneumothorax in trauma patients?
Volume 1 / Issue 102 / 160301
March 1, 2016
What are the most common and serious adverse reactions to oral corticosteroids?
Volume 1 / Issue 103 / 160302
March 1, 2016
Cardiovascular | Acute Coronary Syndrome
Can serial high-sensitivity cardiac troponin T measurement results 1 hour apart accurately diagnose acute myocardial infarction in the emergency department?
Volume 1 / Issue 103 / 160303
March 1, 2016
Can spontaneous subarachnoid hemorrhage be ruled out by modern-generation computed tomography scanning of the brain within 6 hours of acute headache onset?
Volume 1 / Issue 103 / 160304
March 1, 2016
Anesthesia | Procedural Sedation
What are the analgesic and side effects of ketamine-propofol combination (ketofol) in comparison with propofol in procedural sedation and analgesia?
Volume 1 / Issue 103 / 160305
March 1, 2016
Cardiovascular | Acute Coronary Syndrome
Which imaging is most appropriate for emergency department patients with chest pain?
Volume 1 / Issue 104 / 160401
April 1, 2016
Pediatrics | Diabetic Ketoacidosis
Does the volume of intravenous fluid administration influence the time to metabolic normalization in children with type 1 diabetes mellitus and diabetic ketoacidosis?
Volume 1 / Issue 104 / 160402
April 1, 2016
Does ketorolac nasal spray (NS) relieve acute migraine headaches as effectively as sumatriptan NS or placebo within 2 hours?
Volume 1 / Issue 104 / 160403
April 1, 2016
Pediatrics | Procedural Sedation
Which agents are most effective and safest for pediatric procedural sedation?
Volume 1 / Issue 104 / 160404
April 1, 2016
Hematology | Venous Thromboembolism
What are the latest recommendations for the management of venous thromboembolism?
Volume 1 / Issue 104 / 160405
April 1, 2016
Cardiovascular | Cardiac Arrest
Does targeted temperature management of successfully resuscitated cardiac arrest patients by conventional cooling methods improve neurologic outcome or survival?
Volume 1 / Issue 105 / 160501
May 1, 2016
Cardiovascular | Hypotensive Shock
What is the comparative effectiveness of vasopressors on mortality in patients with shock?
Volume 1 / Issue 105 / 160502
May 1, 2016
Which treatments are recommended for status epilepticus?
Volume 1 / Issue 105 / 160503
May 1, 2016
Is prednisone as effective as indomethacin for the treatment of acute gout?
Volume 1 / Issue 105 / 160504
May 1, 2016
Cardiovascular | Congestive Heart Failure
Which are the best tests available to the emergency physician for diagnosing acute heart failure?
Volume 1 / Issue 105 / 160505
May 1, 2016
Can lung ultrasonography reduce chest X-ray use in children with suspected pneumonia?
Volume 1 / Issue 106 / 160601
June 1, 2016
What is the risk of a motor vehicle accident within 2 years of a first-time syncope?
Volume 1 / Issue 106 / 160602
June 1, 2016
Infectious Disease | Skin & Soft Tissue Infection
Does treatment of uncomplicated drained abscesses with trimethoprim-sulfamethoxazole reduce the need for alternate antibiotic therapy or repeat surgical drainage 7–14 days after treatment?
Volume 1 / Issue 106 / 160603
June 1, 2016
Infectious Disease | Skin & Soft Tissue Infection
Do prophylactic antibiotics reduce post-surgical infection for simple hand injuries?
Volume 1 / Issue 106 / 160604
June 1, 2016
Does inhaled magnesium sulfate benefit patients with moderate to severe acute asthma?
Volume 1 / Issue 106 / 160605
June 1, 2016
Can point-of-care testing for group A streptococci in patients presenting with pharyngitis improve appropriate antibiotic prescribing?
Volume 1 / Issue 107 / 160701
July 1, 2016
Does the phosphodiesterase-5 inhibitor sildenafil facilitate passage of distal ureteric stones?
Volume 1 / Issue 107 / 160702
July 1, 2016
Can bedside sonographic measurement of optic nerve sheath diameter in the emergency department identify increased intracranial pressure?
Volume 1 / Issue 107 / 160703
July 1, 2016
Gastrointestinal | Appendicitis
Does antibiotic therapy for non-perforated appendicitis result in more complications compared with appendectomy?
Volume 1 / Issue 107 / 160704
July 1, 2016
Is early goal-directed therapy associated with lower mortality rates than usual care in patients with severe sepsis and septic shock?
Volume 1 / Issue 107 / 160705
July 1, 2016
Is a single-volar digital injection of local anesthetic as effective and less painful than a double-dorsal injection?
Volume 1 / Issue 108 / 160801
August 1, 2016
Is diclofenac more effective at reducing pain from ureteric calculi than morphine or paracetamol?
Volume 1 / Issue 108 / 160802
August 1, 2016
Musculoskeletal | Osteoarthritis
Which nonsteroidal anti-inflammatory drugs are most effective for the treatment of arthritic pain?
Volume 1 / Issue 108 / 160803
August 1, 2016
Which benzodiazepine is most effective for the treatment of status epilepticus in children?
Volume 1 / Issue 108 / 160804
August 1, 2016
Infectious Disease | Skin & Soft Tissue Infection
Is the wound infection cure rate greater with clindamycin than trimethoprim-sulfamethoxazole?
Volume 1 / Issue 108 / 160805
August 1, 2016
Cardiovascular | Cardiac Arrest
Does amiodarone or lidocaine improve survival to hospital discharge after out-of-hospital cardiac arrest due to shock-refractory ventricular fibrillation or pulseless ventricular tachycardia compared to placebo?
Volume 1 / Issue 109 / 160901
September 1, 2016
Infectious Disease | Antibiotic Use
What are the recommendations for antibiotic stewardship?
Volume 1 / Issue 109 / 160902
September 1, 2016
After minimizing heterogeneity in studies reporting the effectiveness of hypertonic saline in bronchiolitis, does hypertonic saline reduce hospital length-of-stay?
Volume 1 / Issue 109 / 160903
September 1, 2016
Does a deliberately restricted laryngeal view with the GlideScope® video laryngoscope facilitate tracheal intubation?
Volume 1 / Issue 109 / 160904
September 1, 2016
Is intra-arterial mechanical thrombectomy safe and effective in patients with ischemic stroke?
Volume 1 / Issue 109 / 160905
September 1, 2016
Is video laryngoscopy superior to direct laryngoscopy for the endotracheal intubation of cardiac arrest patients?
Volume 1 / Issue 110 / 161001
October 1, 2016
How should well-appearing children under 2 years old with fever be managed in the emergency department?
Volume 1 / Issue 110 / 161002
October 1, 2016
Infectious Disease | Pharyngitis
Which are the most diagnostic features of infectious mononucleosis?
Volume 1 / Issue 110 / 161003
October 1, 2016
Is a single oral dose of dexamethasone non-inferior to 5 days of oral prednisone in preventing asthma relapse?
Volume 1 / Issue 110 / 161004
October 1, 2016
Can children with mild gastroenteritis be as effectively treated with initial oral rehydration treatment using dilute apple juice compared to oral electrolyte maintenance solution?
Volume 1 / Issue 110 / 161005
October 1, 2016
Are alpha2-adrenergic agonists effective treatment for opioid withdrawal?
Volume 1 / Issue 111 / 161101
November 1, 2016
What are the risks and benefits of antiepileptic drug treatment for first unprovoked seizure?
Volume 1 / Issue 111 / 161102
November 1, 2016
Thrombosis | Pulmonary Embolism
What is the efficiency and failure rate of diagnostic strategies for ruling out pulmonary embolism?
Volume 1 / Issue 111 / 161103
November 1, 2016
Musculoskeletal | Pelvic Fracture
Are pelvic circumferential compression devices safe and effective for the treatment of pelvic fractures?
Volume 1 / Issue 111 / 161104
November 1, 2016
Gastrointestinal | Appendicitis
Can antibiotics be used as first line therapy for uncomplicated acute appendicitis?
Volume 1 / Issue 111 / 161105
November 1, 2016
What are the early secondary prevention benefits of aspirin after transient ischemic attack or ischemic stroke?
Volume 1 / Issue 112 / 161201
December 1, 2016
Pediatrics | Procedural Sedation
Which is the most effective dose of intravenous ketamine for pediatric procedural sedation and analgesia in the emergency department?
Volume 1 / Issue 112 / 161202
December 1, 2016
Pediatrics | Unexpained Events
How should emergency physicians manage infants with brief resolved unexplained events?
Volume 1 / Issue 112 / 161203
December 1, 2016
Infectious Disease | Influenza
What are the benefits and harms of neuraminidase inhibitors for the prevention and treatment of influenza, and what was their impact on mortality during the 2009A/H1N1 influenza epidemic?
Volume 1 / Issue 112 / 161204
December 1, 2016
What is the relative efficacy of intensive versus standard antihypertensive treatment in patients with spontaneous supratentorial intracerebral hemorrhage?
Volume 1 / Issue 112 / 161205
December 1, 2016