Does procedural sedation with ketofol produce fewer recovery reactions than ketamine?

BEEM Bottom Line

Why is this study important?

Ketamine is frequently used in the emergency department (ED) for procedural sedation and analgesia (PSA) but can induce adverse emergence reactions. This study examines whether the simultaneous administration (1:1 ratio) termed “ketofol,” results in a reduction in emergence reactions compared to using ketamine alone.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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