Does oxygen via high-flow nasal cannula improve symptom relief compared to conventional oxygen therapy in palliative patients presenting with acute hypoxemic respiratory failure?

BEEM Bottom Line

Why is this study important?

Room air and conventional oxygen therapy (COT) via nasal cannula may be ineffective at relieving dyspnea severity in palliative patients.[1] High-flow nasal cannula (HFNC) has been shown to be noninferior to bilevel positive airway pressure (BIPAP) at relieving dyspnea in palliative patients, but it is unknown whether it is superior to COT.[2]

Which, if any, threats to validity are most likely to have an impact on the results and how?

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