Which vasopressors are associated with the best outcomes for adults in cardiac arrest?

BEEM Bottom Line

Why is this study important?

Epinephrine is recommended as the first line medication in the treatment of cardiac arrest.[1] However, the evidence for this recommendation is weak and outdated. More recent evidence suggests that epinephrine may be associated with worse outcomes.[2] This network meta-analysis examines the evidence from all randomized controlled trials (RCTs) of vasopressor drugs for cardiac arrest in adults.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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