Can antibiotics be used as first line therapy for uncomplicated acute appendicitis?

BEEM Bottom Line

Why is this study important?

Acute appendicitis is traditionally treated surgically. There are several reported trials that suggest that antibiotic (Abx) treatment may be an effective alternative, but Abx treatment of acute appendicitis has not been widely adopted.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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