Which medications are associated with adverse events in procedural sedation for children?

BEEM Bottom Line

Why is this study important?

Procedural sedation and analgesia (PSA) is routinely practiced in pediatric emergency departments (ED) yet there is a lack of quality data regarding serious adverse event (SAE) rates specific to this setting or with specific sedating agents. This is the largest study to date that prospectively considers these outcomes specifically within the pediatric ED setting.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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