In out-of-hospital cardiac arrest patients, does a supraglottic airway device improve favorable functional outcome at 30 days compared with endotracheal intubation?
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Why is this study important?
The AIRWAYS-2 trial is the largest randomized controlled trial (RCT) of airway management in out-of-hospital cardiac arrest (OHCA). It compared paramedic use of the iGel supraglottic airway (SGA) to endotracheal intubation (ETI) in the United Kingdom (UK). Concerns with cardiac compression interruptions with ETI, and relatively high SGA success rate without cardiac compression interruptions lead to recommendations to consider SGAs. The relative superiority of ETI or SGAs had been debated, but there has been no direct RCT evidence to make an informed decision.
Which, if any, threats to validity are most likely to have an impact on the results and how?
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