Does early administration of tranexamic acid reduce death in women with post-partum hemorrhage?

BEEM Bottom Line

Why is this study important?

Post-partum hemorrhage (PPH) is the leading cause of maternal death worldwide. Tranexamic acid (TXA) is an inexpensive thrombotic agent proven to reduce mortality in trauma patients in all hospital settings. This trial evaluates the effects of TXA in PPH.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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