Does application of the pulmonary embolism rule-out criteria rule result in an inferior rate of thromboembolic events over 3 months among very low-risk patients with suspected pulmonary embolism?

BEEM Bottom Line

Why is this study important?

The pulmonary embolism (PE) rule-out criteria (PERC) rule was derived to identify patients with a low clinical probability of PE in whom further testing would not be in the patient’s best interest. This study seeks to determine if the PERC is inferior to clinical gestalt in ruling out PE or reducing resource utilization.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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