Can serial high-sensitivity cardiac troponin T measurement results 1 hour apart accurately diagnose acute myocardial infarction in the emergency department?

BEEM Bottom Line

Why is this study important?

This study adds to the growing body of evidence that serial high-sensitivity troponin (hs-cTn) assays can rule out acute myocardial infarction (AMI) within 1–2 hours (h) of emergency department (ED) arrival in patients with acute chest pain.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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