What is the comparative effectiveness of antiarrhythmics for out-of-hospital cardiac arrest for patients with refractory ventricular fibrillation?
BEEM Bottom Line
Why is this study important?
Despite advances in emergency care, survival for out-of-hospital cardiac arrest (OHCA) is poor, with only 1 in 5 persons with ventricular tachycardia/fibrillation (V-tach/V-fib) surviving to hospital discharge. Identifying an intervention that improves return of spontaneous circulation (ROSC), survival to admission, and survival to discharge is important.
Which, if any, threats to validity are most likely to have an impact on the results and how?
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