Is antacid therapy alone more effective than combined with lidocaine in relieving epigastric pain?

BEEM Bottom Line

Why is this study important?

Epigastric pain is a common presenting problem in the emergency department (ED). With a broad differential, the clinician has to exclude several life-threatening causes and manage the patient’s symptoms while awaiting test results. Not infrequently, a trial of antacids with or without local anesthetic is used for pain relief. This study looked at monotherapy antacid versus combination with lidocaine for symptom management.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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