Is 2 days of dexamethasone for children with acute asthma less effective than 5 days of prednisone?

BEEM Bottom Line

Why is this study important?

Dexamethasone (DEX) is often used for asthma exacerbations in children, but its effectiveness compared to prednisone (PRED) is uncertain. This trial uses an inferiority design to assess the comparative effectiveness of symptom resolution.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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