Can a low concentration of high-sensitivity cardiac troponin T at emergency department presentation, combined with the history and electrocardiogram rule out major adverse cardiac events within 30 days?

BEEM Bottom Line

Why is this study important?

High-sensitivity troponin assays will soon replace current generation troponins in most emergency departments (EDs). Because these new assays detect lower troponin concentrations and with reduced variation, emergency physicians can consider newer methods of application in clinical decision-making.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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