What is the risk for emergency neurosurgery or death in children with isolated skull fractures?

BEEM Bottom Line

Why is this study important?

There is widespread practice variation in the management of children diagnosed with an isolated, non-displaced skull fracture. Specifically, many children are admitted for observation out of concern for the potential outcome of neurologic deterioration or death. The risk of these events is only from separate studies and although presumably very low, is not yet known. The investigators attempt to calculate the risk for emergency neurosurgery or death in children with isolated skull fractures by conducting a systematic review and meta-analysis (SRMA).

Which, if any, threats to validity are most likely to have an impact on the results and how?

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