Is topical tranexamic acid effective for anterior epistaxis in patients taking antiplatelet therapy?

BEEM Bottom Line

Why is this study important?

Anticoagulants and antiplatelet medications are commonly used by our aging population, and they are associated with more severe and recurrent epistaxis.[1] Withholding these medications can be harmful. This trial examines the effectiveness of topical tranexamic acid (TXA) for emergency department (ED) patients with anterior epistaxis who are on antiplatelet therapy.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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