Does apneic oxygenation via nasal cannula increase the lowest arterial oxygen saturation experienced by patients undergoing endotracheal intubation?

BEEM Bottom Line

Why is this study important?

Although apneic oxygenation has been advocated for use in emergent intubations outside of the operating room, it has largely been based on nonrandomized trials with high levels of bias, and its effectiveness in the critically ill remains unclear.[1][2] This is the first randomized, prospective trial of apneic oxygenation for patients undergoing emergent intubation in a medical intensive care unit (ICU).

Which, if any, threats to validity are most likely to have an impact on the results and how?

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