Which early rule-out strategy for early rule-out acute myocardial infarction using high-sensitivity cardiac troponin I should be favored for clinical implementation in routine care?

BEEM Bottom Line

Why is this study important?

Multiple rule-out clinical decision tools have been proposed for emergency department (ED) patients with suspected acute myocardial infarction (AMI), and this is the first direct comparison of 4 recent tools in a multi-center study.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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