Do intravenous first-line benzodiazepines terminate seizures faster than non-intravenous routes?

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Why is this study important?

The failure of anticonvulsive treatment and the risk of morbidity and mortality from seizures increase with seizure duration. While the intravenous (IV) delivery of benzodiazepines (BZD) is the most direct and reliable route, non-IV administration of BZDs may be more effective due to more rapid administration.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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