Can patients with large ureteric stones benefit from treatment with alpha-blockers?

BEEM Bottom Line

Why is this study important?

Alpha-blockers, specifically tamsulosin, have become a standard of care as medical expulsive therapy (MET) for patients suffering from ureteric calculi, although an increasing number of trials have failed to show benefit compared to placebo.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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