Are there benefits or harms in treating asymptomatic bacteriuria?

BEEM Bottom Line

Why is this study important?

Rarely does asymptomatic bacteriuria (ABU) progress to severe urinary tract infection (UTI), so the benefits of antibiotic treatment must be weighed against the harms. The most recent guidelines on ABU by the Infectious Disease Society of America (IDSA) were published in 2005.[1] This review is part of the European Association of Urology 2017 guideline update, which specifically examines the evidence of ABU treatment in different patient populations.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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