Is there benefit of antibiotics following incision and drainage of uncomplicated skin abscesses?

BEEM Bottom Line

Why is this study important?

In the pre-methicillin-resistant Staphylococcus aureus (MRSA) era, there was no role for adjuvant antibiotic (Abx) therapy following incision and drainage (I&D) of soft tissue abscesses. Several recent trials studying Abx active against MRSA have shown increased cure rates and decreased recurrence when used in addition to I&D. This network meta-analysis pools these results to quantify the benefit and associated harms.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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