Does oral prednisolone reduce symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection?

BEEM Bottom Line

Why is this study important?

Corticosteroids (CS) have shown benefit for patients with asthma exacerbations and are prescribed for a variety of respiratory illnesses with varying levels of evidence. Inhaled CSs are increasingly prescribed for acute lower respiratory tract infection (LRTI), however, this is the first trial examining the use of oral CS for LRTI in nonasthmatic adults.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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