Does dextrose in intravenous fluids benefit dehydrated children?

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Why is this study important?

Dehydration secondary to gastroenteritis accounts for approximately 10% of pediatric hospital admissions.[1] Due to lower glycogen stores and increased brain energy requirements, children are more likely than adults to become ketotic during times of low carbohydrate intake. In acute gastroenteritis, this condition may result in more marked acidosis and hypoglycemia.[2] This study aims to answer whether administering intravenous (IV) fluids containing dextrose to dehydrated children improves clinical outcomes in non-hospitalized patients.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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