Volume 1 / Issue 103 / 160303
March 1, 2016
Can spontaneous subarachnoid hemorrhage be ruled out by modern-generation computed tomography scanning of the brain within 6 hours of acute headache onset?
Volume 1 / Issue 104 / 160402
April 1, 2016
Does ketorolac nasal spray (NS) relieve acute migraine headaches as effectively as sumatriptan NS or placebo within 2 hours?
Volume 1 / Issue 105 / 160502
May 1, 2016
Which treatments are recommended for status epilepticus?
Volume 1 / Issue 106 / 160601
June 1, 2016
What is the risk of a motor vehicle accident within 2 years of a first-time syncope?
Volume 1 / Issue 107 / 160702
July 1, 2016
Can bedside sonographic measurement of optic nerve sheath diameter in the emergency department identify increased intracranial pressure?
Volume 1 / Issue 109 / 160904
September 1, 2016
Is intra-arterial mechanical thrombectomy safe and effective in patients with ischemic stroke?
Volume 1 / Issue 111 / 161101
November 1, 2016
What are the risks and benefits of antiepileptic drug treatment for first unprovoked seizure?
Volume 1 / Issue 111 / 161105
November 1, 2016
What are the early secondary prevention benefits of aspirin after transient ischemic attack or ischemic stroke?
Volume 1 / Issue 112 / 161204
December 1, 2016
What is the relative efficacy of intensive versus standard antihypertensive treatment in patients with spontaneous supratentorial intracerebral hemorrhage?
Volume 2 / Issue 201 / 170101
January 1, 2017
Neurology | Subarachnoid Hemorrhage
Which patient characteristics and investigations are most accurate for diagnosing subarachnoid hemorrhage?
Volume 2 / Issue 201 / 170105
January 1, 2017
Do corticosteroids improve recovery of facial motor function in patients with Bell’s palsy?
Volume 2 / Issue 203 / 170302
March 1, 2017
What are the key recommendations for evaluation of adult patients with suspected transient ischemic attack in the emergency department?
Volume 2 / Issue 203 / 170403
April 1, 2017
What is the prevalence of pulmonary embolism in patients admitted to hospital for first-time syncope?
Volume 2 / Issue 204 / 170405
April 1, 2017
Neurology | Intracerebral Hemorrhage
What are the most recent recommendations for the management of antithrombotic-associated intracranial hemorrhage?
Volume 2 / Issue 209 / 170902
September 1, 2017
Do intravenous first-line benzodiazepines terminate seizures faster than non-intravenous routes?
Volume 3 / Issue 303 / 180304
March 1, 2018
Neurology | Subarachnoid Hemorrhage
How well does the Ottawa Subarachnoid Hemorrhage Rule detect or rule out subarachnoid hemorrhage?
Volume 3 / Issue 308 / 180803
August 1, 2018
In patients presenting to the emergency department with syncope, what is the prevalence of pulmonary embolism and venous thromboembolism at first evaluation and within 90 days?
Volume 3 / Issue 310 / 181003
October 1, 2018
In acute ischemic stroke and high-risk transient ischemic attack patients, does the addition of clopidogrel to daily aspirin reduce the risk of major ischemic vascular events at 90 days?
Volume 4 / Issue 402 / 190202
February 1, 2019
Neurology | Cerebral vein thrombosis
Is treatment of central venous thrombosis more effective and safer with low-molecular weight or unfractionated heparin?
Volume 4 / Issue 404 / 190403
April 1, 2019
What are the benefits and risks of dual antiplatelet treatment for acute minor ischemic stroke or high risk transient ischemic attack?
Volume 4 / Issue 405 / 190501
May 1, 2019
Does clopidogrel with aspirin compared to aspirin alone given in the first 24 hours after a high-risk transient ischemic attack or minor ischemic stroke reduce recurrent stroke and death?
Volume 4 / Issue 408 / 190801
August 1, 2019
What proportion of syncopal episodes are caused by pulmonary embolism?
Volume 4 / Issue 408 / 190803
August 1, 2019
What are the relative risks of stroke and bleeding in patients with paroxysmal versus sustained (persistent or permanent) atrial fibrillation who take oral anticoagulants?
Volume 4 / Issue 409 / 190901
September 1, 2019
What is the diagnostic yield of computed tomography for patients presenting to the ED with syncope or patients hospitalized for syncope?
Volume 4 / Issue 409 / 190905
September 1, 2019
Which clinical findings best indicate a cardiac or non-cardiac cause of syncope?
Volume 4 / Issue 412 / 191202
December 1, 2019
Does thrombolysis benefit patients with favorable perfusion imaging 4.5–9 hours after stroke onset?
Volume 5 / Issue 504 / 200403
April 8, 2020