What are the risks and benefits of antiepileptic drug treatment for first unprovoked seizure?

BEEM Bottom Line

Why is this study important?

Seizure is a common presenting complaint to the emergency department (ED), comprising approximately 1% of emergency department (ED) visits, and one-quarter of these visits are due to a first episode seizure.[1][2] There is a lack of agreement regarding antiepileptic drug (AED) therapy.

Which, if any, threats to validity are most likely to have an impact on the results and how?

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